Sep
TL;DR: There is no single “best” acne scar treatment, because there’s no single kind of acne scar. The clearest proof is a finding most clinics never mention: the same fractional laser that improved boxcar scars by a median 59% improved icepick scars by only 19%. Meanwhile, RF microneedling now matches CO2 laser for overall scar improvement with a fraction of the downtime, and adding PRP to microneedling roughly triples the odds of a major result. The order of operations matters too — active acne gets treated first, scars second. So the real first step isn’t picking a machine. It’s a diagnosis of what type of scars you actually have.
Acne itself affects 9.4% of the global population — the 8th most prevalent disease on Earth (British Journal of Dermatology, 2015). The scars it leaves behind are what bring many patients to my Guelph practice years after the breakouts stopped. And the question I hear most is some version of: “Which treatment actually works?”
In my experience, that’s the wrong first question. The right one is: which scars do you have? Because the evidence is unusually clear that scar type predicts treatment response better than almost anything else.
Key Takeaways
- Scar type changes everything: 1550nm fractional laser reduced boxcar scars by a median 59% but icepick scars by only 19% (Dermatology and Therapy, 2023).
- RF microneedling matched fractional CO2 laser for atrophic acne scars (~44% vs ~42% improvement) with faster recovery and fewer pigment problems in a 2026 randomized split-face trial (Journal of Dermatological Treatment, 2026).
- Adding PRP to microneedling roughly triples the odds of a greater-than-50% improvement (Frontiers in Medicine meta-analysis, 2022).
- In deeper skin tones, post-inflammatory pigmentation — not the scar itself — is often the bigger concern: after acne, 65.3% of African-American patients developed dark marks in one US study (JCAD review).
The answer determines your treatment plan, so let’s define the players. Dermatologists group atrophic acne scars — the sunken kind, by far the most common — into three shapes:
There’s a fourth category worth naming: post-inflammatory hyperpigmentation (PIH) — the flat dark marks acne leaves behind. Strictly speaking, PIH isn’t a scar at all, and it often fades or clears with pigment-directed treatment rather than resurfacing. That distinction matters most in deeper skin tones: in one frequently cited US study, 65.3% of African-American acne patients and 52.7% of Hispanic patients developed PIH (Journal of Clinical and Aesthetic Dermatology review). If your “scars” are flat and brown rather than indented, you may need a pigment plan, not a laser plan.
Most people have a mix. Which is precisely why a one-machine-fits-all clinic is a red flag.
Because the same treatment can succeed and fail on the same face. In a 2023 analysis of 1550nm fractional laser treatment, boxcar scars improved by a median 59% — while icepick scars improved by only 19% (Dermatology and Therapy, 2023). Same laser, same patients, three-fold difference in outcome purely by scar shape.
Consequently, icepick scars usually need targeted techniques — chemical reconstruction applied pit-by-pit, or punch excision of individual scars — before any resurfacing pass. Rolling scars often respond to subcision, releasing the fibrous bands that tether them, which resurfacing alone doesn’t address. The devices get the marketing budget; the diagnosis does the heavy lifting.
For the resurfacing workhorses, the head-to-head data has genuinely shifted. In a 2026 randomized split-face trial, RF microneedling matched fractional CO2 laser for atrophic acne scars — roughly 44% versus 42% scar-score reduction over three sessions — while producing shorter redness, less swelling, and fewer pigment problems (Journal of Dermatological Treatment, 2026). A 2025 systematic review of 16 studies and 481 patients confirmed RF microneedling works as a standalone scar treatment (Clinical, Cosmetic and Investigational Dermatology, 2025).
However, CO2 still earns its place. Fractional CO2 typically delivers 30-70% scar improvement over 2-4 sessions (Life, systematic review, 2025), and for deep, etched, sun-damaged skin it remains the deep remodeler. The trade is roughly five days of downtime and a higher pigmentation risk — manageable with protocol, but real. For the full comparison, including Fraxel-type lasers and how we sequence them, see our resurfacing decision guide.
Meanwhile, PRP (platelet-rich plasma) has earned amplifier status: a 2022 meta-analysis found that adding PRP to microneedling roughly tripled the odds of achieving a greater-than-50% scar improvement (Frontiers in Medicine, 2022). PRP rarely stands alone for scars — it makes a good plan better.
For skin of color, the safety hierarchy matters as much as the efficacy one. Across 35 studies of RF and RF microneedling in medium-to-deep skin tones, reported pigment changes were transient in nearly every case (Dermatologic Surgery, 2023) — one reason RF microneedling, including Morpheus8, is often my first-line recommendation for deeper skin tones where ablative lasers carry more PIH risk.
Acne first — almost always. Treating scars while breakouts continue is repaving a road that’s still under construction: new inflammation keeps creating new scars behind the treatment, and active lesions raise the complication risk of energy-based procedures.
For instance, if you’re still getting monthly cystic flares, the highest-value first step is medical acne treatment — often covered by OHIP when a physician treats the disease itself, as we’ve explained in our medical vs. cosmetic acne guide. Stabilize the acne, let the skin quiet down, then map the scars that remain. There’s also an interesting wrinkle in newer data: in a 356-patient study, acne treated with RF microneedling showed a 24% three-year relapse rate versus 67% with isotretinoin — though its authors are device-company consultants, so treat those numbers as promising rather than definitive (Aesthetic Surgery Journal, 2025). Some treatment plans now address active acne and early scarring with the same device family.
Here’s the honest shape of it, in my experience:
Ready to find out which scars you actually have? Request a consultation and we’ll build the map before we ever talk devices.
There isn’t one — and that’s the evidence talking, not hedging. The same fractional laser improved boxcar scars 59% but icepick scars only 19% (Dermatology and Therapy, 2023). The best treatment is the one matched to your scar types after assessment.
No treatment erases scars completely, and clinics claiming otherwise are overpromising. Published benchmarks show 30-70% improvement with fractional CO2 over 2-4 sessions (Life, 2025) and ~44% with RF microneedling over three (JDT, 2026). Substantial, visible — not total.
For overall improvement they now test as equals: ~44% vs ~42% in a 2026 randomized split-face trial (Journal of Dermatological Treatment, 2026). RF microneedling recovers faster with fewer pigment issues; CO2 reaches deeper etched damage. Skin tone, scar depth, and downtime tolerance decide it.
As an amplifier, yes. A 2022 meta-analysis found adding PRP to microneedling roughly tripled the odds of a greater-than-50% improvement (Frontiers in Medicine, 2022). On its own it’s rarely the plan; alongside microneedling it meaningfully raises the ceiling.
With the right device choice, yes. Across 35 studies in medium-to-deep skin tones, pigment changes after RF microneedling were transient in nearly every reported case (Dermatologic Surgery, 2023). Ablative lasers carry more pigmentation risk and need conservative settings — one more reason assessment comes first.
Medically reviewed by Dr. Dusan Sajic, MD, PhD — dermatologist, deRMA Skin Institute, Guelph, ON.
1. Tan JKL, Bhate K, “A global perspective on the epidemiology of acne,” British Journal of Dermatology, 2015, https://pubmed.ncbi.nlm.nih.gov/25597339/ 2. Randomized split-face trial, RF microneedling vs fractional CO2 for atrophic acne scars, Journal of Dermatological Treatment, 2026, https://pubmed.ncbi.nlm.nih.gov/42312398/ 3. Scar-type response analysis (boxcar vs icepick, 1550nm fractional laser), Dermatology and Therapy, 2023, https://pmc.ncbi.nlm.nih.gov/articles/PMC9884716/ 4. Fractional CO2 for acne scars, systematic review, Life (MDPI), 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC12194615/ 5. Microneedling with PRP for atrophic acne scars, meta-analysis, Frontiers in Medicine, 2022, https://pmc.ncbi.nlm.nih.gov/articles/PMC8882957/ 6. RF microneedling as standalone acne-scar treatment, systematic review, Clinical, Cosmetic and Investigational Dermatology, 2025, https://pubmed.ncbi.nlm.nih.gov/39781098/ 7. RF and RF microneedling in skin of color, 35-study review, Dermatologic Surgery, 2023, https://journals.lww.com/dermatologicsurgery/abstract/2023/05000/radiofrequency_and_radiofrequency_microneedling_in.10.aspx 8. Taylor SC et al., acne in skin of color / PIH epidemiology, via JCAD review, https://jcadonline.com/postinflammatory-hyperpigmentation-a-review-of-the-epidemiology-clinical-features-and-treatment-options-in-skin-of-color/ 9. Three-year acne relapse comparison (RF microneedling vs isotretinoin; authors are device-company consultants), Aesthetic Surgery Journal, 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC11736774/
Dusan Sajic, MD, PhD
Richard Backstein, MD
Sonja Sajic, CCPA
Toni Alberto, CCPA
With more than 20 years of experience, deRMA Skin Institute strive to offer patients the most advanced treatments available to keep their skin healthy and looking its best. Board Certified Dermatologist, Dusan Sajic, MD, PhD, board-certified Plastic and Reconstructive Surgeon, Richard Backstein, MD, FRCSC, Sonja Sajic, CCPA, and Toni Alberto CCPA are committed to providing state-of-the-art medical, surgical and cosmetic treatments to all patients in Guelph, Cambridge, Kitchener, Hamilton, Milton, and surrounding areas.
Fields marked * are required
If you are an existing patient inquiring about appointments and services, please contact
Guelph Cosmetic Department: (888) 803-3762 cosmetic@dermaskininstitute.com
Guelph Medical Department: (519) 836-8558 patientcare@dermaskininstitute.com