Treatment: Botox®/Dysport®/Xeomin®
Indications: Wrinkles, folds, fine lines
Best Results Seen: 6 months or longer post final treatment
Treatment Recovery: Immediate
# Of Treatments Required: Every 3-4 months
Do people often ask if something’s bothering you even when you’re feeling content? Or do you feel like the face you see in the mirror doesn’t reflect the youthful vitality you feel? BOTOX injections at our Guelph and Burlington clinics can minimize early signs of aging, such as forehead wrinkles, worry lines, and crow’s feet. Women and men considering BOTOX travel from Kitchener-Waterloo, Oakville, and throughout Southern Ontario to deRMA Skin Institute to have experienced, board-certified dermatologists perform the treatments.
See For Yourself

Case #79
Procedure(s): BOTOX®, Dermal Fillers, Radiesse®, eCO2™ Laser Skin Resurfacing, Dilute Radiesse®
Keep in mind that each patient is unique and your results may vary.
Derma Skin Institute is a medical and cosmetic dermatology practice in Guelph and Burlington that serves the Southern and Southwestern Ontario areas. Dr. Dusan Sajic, Dr. Richard Backstein, Dr. Daniel Wong, and Dr. Tiffany Chen are certified by the Royal College of Physicians and Surgeons of Canada. Dr. Sajic performs a range of anti-aging skincare treatments which include, but are not limited to laser skin tightening, CO2 skin resurfacing, AccuTite, Dysport, Botox, Radiesse, Sculptra, and platelet-rich plasma (PRP) treatment. Derma Skin Institute also offers radiofrequency microneedling and lasers to target concerns such as acne scarring, rosacea, sun damage, among other procedures. Women and men seeking dermatology treatments from the GTA to London and surrounding area choose deRMA Skin Institute.
What are BOTOX®, Dysport®, and XEOMIN®?
These three products are called “neuromodulators”, injectable treatments that work by relaxing the muscles responsible for fine lines and folds. While BOTOX is the most well-known of these three treatments, all three products––BOTOX, Dysport, and XEOMIN––contain the same primary active ingredient for wrinkle reduction: botulinum toxin type A. The main difference between each injectable is the protein presence in each formula that affects the way they blend, interact, or smooth when administered. These injections temporarily block the nerve impulses that cause the muscles to contract and crease the skin. As a result, lines are smoother and prevented from deepening.
What do BOTOX®, Dysport®, and XEOMIN® treat?
These neuromodulators can offer effective treatment for any concerns affected by muscle contractions. The most common treatment areas are around the forehead and eyes, including forehead lines, frown lines (glabellar lines), bunny lines on the sides of the nose, “11s” (those vertical lines between the eyebrows), crow’s feet or smile lines, some dimples, and other concerns along the neck, chest, or jawline. BOTOX®, Dysport®, and XEOMIN® also have non-cosmetic applications for concerns like migraines, jaw clenching, and more.
How does it work?
BOTOX, Dysport, and XEOMIN treat visible lines and wrinkles by inhibiting the contractions causing them. These repeated movements occur whenever our faces change expressions, such as squinting, frowning, or smiling. Every time you squint, you’re creating or deepening a line, in the same way that a piece of paper creases when repeatedly folded in the same direction. As we get older, our body’s natural collagen and elastin stores decline and skin may be more thin, less voluminous, and more likely to crease or sag easily. By relaxing the muscles that create folds and wrinkles, we can smooth skin for a more youthful appearance
Why Choose Derma Skin Institute?
Even though BOTOX®, Dysport®, and XEOMIN® injections are common, your results will only be as good as the injector performing them. At our clinic, you will always be assessed by a board-certified dermatologist and injectable expert to make sure our treatments align with your goals and improve your skin health. We pride ourselves on creating personalized and customized treatments for your unique features. That includes combining BOTOX, Dysport, or XEOMIN with other aesthetic procedures as part of Dr. Sajic’s 5 Dimensions Skin Plan™ to consider the whole face, instead of “quick fix” approaches that miss the way your features affect each other. Our providers customize doses and inject with precision using a conservative approach that prevents the “frozen” appearance often produced by inexperienced injectors.
You can expect:
- Personalized treatments customized to your skin type, goals, unique features, and concerns.
- A legacy of expertise, gallery of real patient Before and After Results, and skin wisdom to craft a beautiful result.
- Natural-looking results that enhance the best aspects of your aesthetic.
- Minimal downtime with a non-invasive procedure that doesn’t require booking time off.
- At our clinic, you will always be assessed by a board-certified dermatologist.
- Dr. Sajic is a board-certified medical and cosmetic dermatologist, and the visionary director of the Derma Skin Institute, at the forefront of advancing injectable technique and innovation.
- We’re locally trusted for our longstanding reputation, patient loyalty, and consistent delivery of beautiful outcomes across Guelph and Burlington—drawing patients from Dundas, Oakville, Toronto, Waterdown, and beyond who seek advanced care and exceptional results.
Frequently Asked Questions (FAQ)
How long do results last?
BOTOX®, Dysport®, and XEOMIN® results typically last 3-6 months. The lasting time of your results depends on the volume of neuromodulator used, the size of the targeted area, and your unique facial anatomy. As your muscles and movements change with time, your treatment plan and dosing may also need to change. Your face is uniquely yours and your treatment plan should be too!
Can any wrinkles be treated with BOTOX®, Dysport®, and XEOMIN® neuromodulators?
These products are most effectively used on dynamic wrinkles, which differ from depleted volume, hollow tear troughs, and/or cheek fullness. Some lines and wrinkles are caused by the natural aging process, sun damage, and gravity, and may be best treated with a combination treatment plan to restore lost volume and spark collagen production.
What does treatment feel like?
We prioritize comfort, safety,and a pleasant experience for all of our patients from consultation through to beautiful results. We find that most patients tolerate filler injections quite well. We use numbing cream as well as a local anaesthetic to help keep you comfortable. Additionally, a local anaesthetic, such as lidocaine, is pre-mixed with many injectable treatments. If needed, we may also medicate you with prescription-strength pain medicine. We also have Penthrox® as an option—an effective, fast-acting, non-opioid inhaled analgesic product that helps greatly with pain and anxiety.
Always communicate any pain or discomfort to your provider, and we will be happy to adjust your treatment appropriately.
Can I combine BOTOX®, Dysport®, and XEOMIN® with other treatments?
Yes! Using different injectable treatments in intentional, artful combinations is one element of Dr. Sajic’s 5 Dimension Skin Plan™— you can learn more about that here. We may customize a treatment plan that targets multiple concerns in one treatment regimen or procedure. Neuromodulators like Botox® can be effectively paired with dermal fillers to combine the smoothing, relaxing, and preventative properties of both treatments. We may address wrinkles, treat the lips and also address undereye circles, contour the jawline or nose, and other volume-related concerns in one treatment.
How are neuromodulators like Botox® different from dermal fillers?
Both treatments are injectables, but neuromodulators act to relax the muscles causing wrinkles or folds. This can have preventative effects; neuromodulators keep lines and folds from forming and deepening by decreasing the repeated movements that cause them. But they also actively smooth existing folds.
Is there downtime needed?
No, non-invasive injectable neuromodulators like BOTOX®, Dysport®, and XEOMIN® have long-lasting results without any needed downtime.
Book your free consultation
We look forward to seeing you for BOTOX®, Dysport®, and XEOMIN® treatment in our Guelph or Burlington clinics. Patients from Kitchener, Cambridge, Hamilton, Oakville, Milton, Mississauga, and surrounding areas across Southwestern Ontario choose Derma Skin Institute for their injectable treatments.
Request a consultation using the online form or call us at (888) 803-3762 to schedule an appointment with one of our dermatologists.

Dusan Sajic, MD, PhD

Richard Backstein, MD

Sonja Sajic, CCPA

Daniel Wong, MD, FRCPC

Tiffany Chen, MD, FRCPC, DABD

Toni Alberto, CCPA
With more than 20 years of experience, deRMA Skin Institute strive to offer patients the most advanced treatments available to keep their skin healthy and looking its best. Board Certified Dermatologist, Dusan Sajic, MD, PhD, board-certified Plastic and Reconstructive Surgeon, Richard Backstein, MD, FRCSC, Sonja Sajic, CCPA, Toni Alberto CCPA, Tiffany Chen MD PRCPC and Daniel Wong MD FRCPC are committed to providing state-of-the-art medical, surgical and cosmetic treatments to all patients in Guelph, Burlington, Cambridge, Kitchener, Hamilton, Milton, and surrounding areas.